New Brain Injury Research Has Been Reported by Researchers at University of the Basque Country (UPV) (Dimethyl Fumarate Strongly Ameliorates Gray and White Matter Brain Injury and Modulates Glial Activation after Severe Hypoxia-Ischemia in...).

A recent study conducted by researchers at the University of the Basque Country (UPV) in Spain has found that dimethyl fumarate (DMF) shows potential as a treatment for neonatal encephalopathy, a condition caused by neonatal hypoxia-ischemia that can lead to infant death and disability. The study used a modified Rice-Vannucci model to induce severe hypoxic-ischemic brain damage in neonatal rats and found that DMF reduced brain tissue loss, improved neuropathological scores, preserved myelin tracts, and reduced astroglial and microglial activation. While further research is needed, this study suggests that DMF could be a promising treatment for neonatal encephalopathy. [Extracted from the article]