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Researchers at University of California Davis Release New Data on Opioids (Deletion of arrestin-3 does not reduce drug-seeking behavior in a longitudinal paradigm of oral morphine self-administration).
- Source :
- Drug Week; 10/18/2024, p2656-2656, 1p
- Publication Year :
- 2024
-
Abstract
- A recent report from researchers at the University of California Davis discusses the use of opioids and the potential for reducing drug-seeking behavior. The study focused on the role of arrestin-3, a protein involved in opioid receptor activation, and its impact on compulsive drug-seeking. The researchers found that mice lacking arrestin-3 did not show reduced drug-seeking behavior, suggesting that its absence does not protect against the abuse liability of opioids. The study suggests that opioids that engage both G protein and arrestin-3 may reduce abuse liability. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 15316440
- Database :
- Supplemental Index
- Journal :
- Drug Week
- Publication Type :
- Periodical
- Accession number :
- 180200786