Findings in Diet and Nutrition Reported from University Hospital Southampton NHS Foundation Trust (Surfactant Phospholipid Kinetics in Ventilated Children after Therapeutic Surfactant Supplementation).

A recent study conducted by researchers at the University Hospital Southampton NHS Foundation Trust in the United Kingdom explored the effects of surfactant supplementation on the composition and metabolism of surfactant lipids in mechanically ventilated pediatric patients. The study utilized a stable isotope labeling technique and found that acute lung injury leads to alterations in surfactant lipid composition and metabolism. The researchers observed variability in surfactant synthesis and secretion among patients, highlighting the need for further investigation in this area. The study was funded by the Nihr Southampton Respiratory Biomedical Research Unit. [Extracted from the article]