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University of Missouri Researcher Releases New Study Findings on Beta-Globulins (Plasminogen Activation Inhibitor-1 Promotes Resilience to Acute Oxidative Stress in Cerebral Arteries from Females).

Source :
Genomics & Genetics Weekly; 10/11/2024, p2301-2301, 1p
Publication Year :
2024

Abstract

A new study conducted by researchers at the University of Missouri explores the role of plasminogen activation inhibitor-1 (PAI-1) in promoting resilience to acute oxidative stress in cerebral arteries, specifically in females. The study found that PAI-1 can limit cell death and mitochondrial depolarization in male mice, while in female mice, the absence of PAI-1 led to increased cell death and mitochondrial depolarization. These findings have implications for stroke treatment and the restoration of blood flow. The study was published in the journal Pharmaceuticals. [Extracted from the article]

Details

Language :
English
ISSN :
15316467
Database :
Supplemental Index
Journal :
Genomics & Genetics Weekly
Publication Type :
Periodical
Accession number :
180073115