Reports from Tehran University of Medical Sciences Advance Knowledge in Optic Nerve Injury (Protective Effects of Sumatriptan Against Optic Nerve Injury In Rats Via Modulation of Kynurenine Pathway, Oxidative Stress and Apoptosis).

A study conducted at Tehran University of Medical Sciences in Iran explored the potential protective effects of sumatriptan against optic nerve injury in rats. Sumatriptan, an antimigraine agent, was found to increase cell survival, improve optic nerve function, and decrease inflammation in the retinas of rats. The researchers suggest that future clinical trials should assess the efficacy of low-dose intravitreal sumatriptan for patients with traumatic optic neuropathy. This study provides valuable insights into potential treatments for optic nerve injury. [Extracted from the article]