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University of Nebraska Medical Center Reports Findings in Cancer (Rhno1: At the Crossroads of Dna Replication Stress, Dna Repair, and Cancer).
- Source :
- Drug Week; 9/6/2024, p1382-1382, 1p
- Publication Year :
- 2024
-
Abstract
- A recent study conducted by the University of Nebraska Medical Center explores the role of DNA replication stress (DRS) response in cancer. The researchers highlight the importance of DRS in maintaining genome integrity and its increased presence in tumor cells. They specifically focus on a protein called Rad9-Hus1-Rad1 Interacting Nuclear Orphan 1 (RHNO1), which plays a role in the DRS response and DNA repair. The study suggests that targeting RHNO1 could hold promise as a therapeutic approach for tumors with elevated DRS and DNA repair deficiencies. Further research into RHNO1's function in cancer is needed to develop novel strategies for cancer treatment. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 15316440
- Database :
- Supplemental Index
- Journal :
- Drug Week
- Publication Type :
- Periodical
- Accession number :
- 179335536