New Nephropathy Research Has Been Reported by Researchers at First Affiliated Hospital of Guangxi Medical University (Predictive value of combining urinary N-acetyl-b-D-glucosaminidase and serum homocysteine for contrast-induced nephropathy in...).

A new report from researchers at the First Affiliated Hospital of Guangxi Medical University in China explores the use of urinary N-acetyl-b-D-glucosaminidase (uNAG) and serum homocysteine (sHCY) as potential predictors for the early detection and prognosis of contrast-induced nephropathy (CIN) in patients after percutaneous coronary intervention (PCI). The study found that the combination of uNAG and sHCY demonstrated better sensitivity and specificity for predicting the diagnosis and prognosis of CIN compared to using either biomarker alone. The panel of uNAG and sHCY also detected CIN earlier than serum creatinine (sCr). However, the combined detection did not significantly enhance the predictive capability for major adverse cardiovascular events (MACE) in patients with CIN. [Extracted from the article]