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Nasal clear cell chondrosarcoma in a dog.
- Source :
- Journal of Comparative Pathology; Aug2024, Vol. 213, p37-40, 4p
- Publication Year :
- 2024
-
Abstract
- An intranasal tumour was diagnosed in a 5-year-old male neutered crossbreed dog following a 6–8 week history of intermittent epistaxis and nasal discharge. Computed tomography identified a mass in the right nasal cavity. Histologically, the mass was composed of sheets and indistinct clusters of predominantly clear or vacuolated round to polygonal cells; periodic acid–Schiff staining revealed glycogen granules within some tumour cells. Immunohistochemical labelling revealed that the tumour cells were immunopositive for vimentin and S100 and negative for pancytokeratin, Melan-A and PNL2, supporting a diagnosis of a clear cell variant of chondrosarcoma (CCC). Although the dog was treated with meloxicam, the owners opted for euthanasia 9 days after presentation. Considering that there is only one other reported case of a suspected CCC in a dog, also in the nasal cavity, this could represent a species-specific predilection site of this rare canine neoplasm. [ABSTRACT FROM AUTHOR]
- Subjects :
- NASAL tumors
NASAL cavity
COMPUTED tomography
CHONDROSARCOMA
GLYCOGEN
Subjects
Details
- Language :
- English
- ISSN :
- 00219975
- Volume :
- 213
- Database :
- Supplemental Index
- Journal :
- Journal of Comparative Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 179240338
- Full Text :
- https://doi.org/10.1016/j.jcpa.2024.06.007