Study Findings from University of California Riverside Provide New Insights into Obesity (Obesity Alters Pomc and Kisspeptin Neuron Cross Talk Leading To Reduced Luteinizing Hormone In Male Mice).

A study conducted by researchers at the University of California Riverside has found that obesity in male mice leads to a reduction in luteinizing hormone (LH), which is associated with hypogonadism. The researchers discovered that obesity affects the regulation of kisspeptin neurons, which play a role in LH secretion. They also found that obesity affects the cross talk between kisspeptin neurons and anorexigenic POMC neurons. These findings provide new insights into the mechanisms behind obesity-related hypogonadism. [Extracted from the article]