New DiGeorge Syndrome Study Findings Have Been Reported from Department of Health of Moscow (Prognostic changes in lymphocyte subpopulations during the development of autoimmune complications in patients with DiGeorge syndrome).

A recent study conducted by the Department of Health of Moscow focused on patients with DiGeorge syndrome, a genetic condition characterized by immunodeficiency. The study aimed to compare the subpopulations of T and B lymphocytes in patients with and without autoimmune complications and identify prognostic signs that precede the development of complications. The researchers found that patients with autoimmune complications had a decrease in certain subpopulations of T and B lymphocytes, such as CD45RA+ naive T cells and memory B cells. These findings suggest that regular immunophenotyping, particularly of these subpopulations, can help predict autoimmune complications in patients with DiGeorge syndrome. [Extracted from the article]