Altered Cortical Network Dynamics during Observing and Preparing Action in Patients with Corticobasal Syndrome.

This article discusses a study on the electrophysiological underpinnings of corticobasal syndrome (CBS), a neurodegenerative disorder characterized by parkinsonism and higher order cortical dysfunctions. The study recorded the brain activity of CBS patients and healthy controls while they engaged in an observe-to-imitate task. The results showed that CBS patients had weaker beta-band (13-30Hz) event-related desynchronization during action observation, suggesting reduced motor cortical disinhibition. The study also found that CBS patients had deficits in embedding observed action into a motor representation and learning the temporal structure of the task. However, it is important to note that this study is a preprint and has not been peer-reviewed. [Extracted from the article]