New Findings in Liposomes Described from University of Leeds (Chitosan-coated liposomal systems for delivery of antibacterial peptide LL17-32 to Porphyromonas gingivalis).

A recent report from the University of Leeds discusses the use of liposomes as a delivery mechanism for antimicrobial peptides to combat periodontal disease caused by Porphyromonas gingivalis. The study examines the different types of liposomal formulations and their ability to associate and deliver the peptide LL17-32 to act against the pathogen. The research found that chitosan-coated liposomes demonstrated enhanced stability and decreased membrane fluidity when combined with LL17-32. However, the release of the peptide was restrained, which could be useful for future slow-release formulations. [Extracted from the article]