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Association between skin suture devices and incidence of incisional surgical site infection after gastrointestinal surgery: systematic review and network meta-analysis.
- Source :
- Journal of Hospital Infection; Aug2024, Vol. 150, p134-144, 11p
- Publication Year :
- 2024
-
Abstract
- Surgical site infections (SSIs) are common complications after abdominal surgery. To compare which suture devices could reduce the incidence of incisional surgical site infections (SSIs) after gastrointestinal surgery using a systematic review and network meta-analysis. The CENTRAL, PubMed, and ICHUSHI-Web databases were searched from January 1<superscript>st</superscript>, 2000, to December 31<superscript>st</superscript>, 2022, for randomized clinical trials (RCTs) comparing the incidence of incisional SSI after gastrointestinal surgery among patients treated with different surgical suture devices, including non-absorbable sutures, absorbable sutures, skin staplers, and tissue adhesives (last searched in August 23<superscript>th</superscript>, 2023). The risk of bias was assessed using the criteria of the Cochrane Handbook for Systematic Reviews of Interventions. To estimate the pooled odds ratios (ORs) for each comparison, a fixed-effect inverse-variance model based on the Mantel–Haenszel approach was employed. A total of 18 RCTs with 5496 patients were included in this study. The overall SSIs in absorbable sutures were significantly lower than those in skin staplers (OR: 0.77; 95% confidence intervals (CI): 0.63–0.95) and non-absorbable sutures (OR: 0.62; 95% CI: 0.39–0.99), whereas SSIs in absorbable sutures were not significantly different from the SSIs in tissue adhesive. The highest P-score was 0.91 for absorbable sutures. A funnel plot for estimating the heterogeneity of the studies revealed that a publication bias would be minimal (Egger test, P = 0.271). This study showed that absorbable sutures reduced incisional SSIs in gastrointestinal surgical operations compared to any other suture devices. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01956701
- Volume :
- 150
- Database :
- Supplemental Index
- Journal :
- Journal of Hospital Infection
- Publication Type :
- Academic Journal
- Accession number :
- 178636719
- Full Text :
- https://doi.org/10.1016/j.jhin.2024.04.029