Reports Summarize Anaphylaxis Findings from Mayo Clinic (A Us-based Multicenter Retrospective Report of Perioperative Anaphylaxis, 2010-2021).

A recent study conducted at the Mayo Clinic in Jacksonville, Florida examined cases of perioperative anaphylaxis (POA) in the United States from 2010 to 2021. The study found that a serum acute tryptase (sAT) level above 9.8 ng/mL or mast cell activation (MCA) can predict the identification of the causal agent in POA. However, urinary mast cell mediator metabolites (uMC) were not found to be associated with the identification of the causal agent. The study suggests using an acute/baseline uMC ratio in patients with inconclusive tryptase levels during POA evaluations. [Extracted from the article]