Research Data from University of Tokyo Update Understanding of Nanocarriers (Enzyme Stability In Polymer Hydrogel-enzyme Hybrid Nanocarrier Containing Phosphorylcholine Group).

A recent study conducted by researchers at the University of Tokyo in Japan explores the use of zwitterionic polymer nanogels as a means to enhance enzyme stability. Enzymes are widely used in various fields but their low stability limits their applications. The researchers synthesized zwitterionic copolymer nanogels and immobilized the enzyme beta-galactosidase within them. The hybrid nanogel-enzymes demonstrated superior stability compared to free enzymes, maintaining their function under harsh conditions such as high temperature and organic solvents. This research suggests that polymer nanogels containing phosphorylcholine units have potential for enzyme immobilization and expanding the scope of enzyme applications. [Extracted from the article]