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New Cancer Study Findings Recently Were Reported by Researchers at King Saud University (The Potential Effect of Tubulysin a On Autophagy In a Group of Cancer Cell Lines).
- Source :
- Cancer Weekly; 7/2/2024, p653-653, 1p
- Publication Year :
- 2024
-
Abstract
- Researchers at King Saud University in Riyadh, Saudi Arabia have conducted a study on the potential effect of Tubulysin A (TubA) on autophagy in a group of cancer cell lines. Autophagy, the process of self-degradation of cellular components, plays a role in cancer development and response to chemotherapy. The study found that TubA, a myxobacteria-derived peptide, demonstrated significant antiproliferative effects on various cancer cell lines at low concentrations. It induced autophagy and triggered an intrinsic apoptotic pathway, leading to cell death in the MCF-7 cancer cell line. This research provides insights into potential therapeutic strategies for cancer treatment. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 10717218
- Database :
- Supplemental Index
- Journal :
- Cancer Weekly
- Publication Type :
- Periodical
- Accession number :
- 178121289