Study Findings on Atopic Dermatitis Described by Researchers at Seoul National University College of Medicine (Impact of fucosyltransferase 1-mediated epidermal blood group antigen H on anti-inflammatory response in atopic dermatitis).

A study conducted by researchers at Seoul National University College of Medicine explores the impact of fucosyltransferase 1-mediated epidermal blood group antigen H on the anti-inflammatory response in atopic dermatitis (AD). The study found that the expression of ABH antigen is primarily located in the granular and horny layers of healthy skin, but is absent or diminished in patients with AD. Additionally, Fut1-deficient mice, which lack H2 antigen expression on their skin, exhibited more severe clinical signs of AD-like inflammation compared to wild-type mice. These findings suggest that H2 antigen expression plays a protective role against AD-like inflammation and may have therapeutic implications for AD treatment. [Extracted from the article]