Analysis of Peripheral Blood Lymphocytes in Patients With Juvenile Idiopathic Arthritis With Respect to Disease Subtypes and Therapy.

The article discusses a clinical trial focused on juvenile idiopathic arthritis (JIA), the most common chronic rheumatic disease in children. The trial aims to analyze peripheral blood lymphocytes in JIA patients to understand disease subtypes and therapy. It explores different subtypes of JIA, the role of immune system cells in JIA, and available treatments such as NSAIDs, DMARDs, and biologic agents. The trial also examines the potential risk of infections associated with these treatments. It highlights that children with JIA may have a higher risk of infection due to their condition and treatments used, but more research is needed on immune cell alterations related to infection control. [Extracted from the article]