Studies from Longyan University Provide New Data on Bioinformatics (Bioinformatics Analysis and Comparison of the S Protein of Canine Coronavirus and Feline Coronavirus).

A study conducted by researchers at Longyan University in China analyzed the spike (S) protein structure and phylogenetic association of Canine Coronavirus (CCoV) and Feline Coronavirus (FCoV) using bioinformatics. The results showed that the S proteins of both viruses contained transmembrane regions and signal peptides, as well as two functional domains and two motifs. Phylogenetic analysis revealed that CCoV-I and FCoV-I were in the same clade, while CCoV-IIb, FCoV-II, and TGEV formed another clade. The findings of this study can contribute to a better understanding of coronavirus S proteins and aid in the development of antiviral drugs and vaccines. [Extracted from the article]