New Tricyclic Antidepressants Study Findings Recently Were Reported by Researchers at Department of Pharmacy [Antinociceptive Antinociceptive Evaluation of Antidepressants (Cita- lopram, Duloxetine and Amitriptyline) in a Mouse Model of Acute...].

A recent study conducted by researchers at the Department of Pharmacy has found that tricyclic antidepressants, specifically Citalopram, Duloxetine, and Amitriptyline, have a significant effect in reducing acute nociceptive pain in mice. The study involved administering these antidepressants to mice and then inducing pain through the injection of acetic acid. The researchers observed a decrease in pain-related behaviors such as writhing and paw licking in the mice treated with these antidepressants. The findings suggest that these antidepressants may have potential as analgesics for acute pain. [Extracted from the article]