"In Vitro Glycoengineering Of Antibodies" in Patent Application Approval Process (USPTO 20240101643).

A patent application by F. Hoffmann-La Roche Inc. outlines a method for modifying the glycosylation of antibodies in vitro. The method involves binding the antibodies to a solid phase and then using glycosylation modifying enzymes to alter the glycosylation. This process can be applied to different types of antibodies and allows for the production of antibodies with specific and controlled glycosylation patterns. The modified antibodies can be recovered and purified for further use. This method is cost-effective and can be easily integrated into existing antibody purification processes. [Extracted from the article]