Studies in the Area of Hypertension Reported from McGill University Health Centre Research Institute (Mechanisms of Vascular Inflammation and Potential Therapeutic Targets: A Position Paper From the ESH Working Group on Small Arteries).

New research from McGill University Health Centre Research Institute explores the role of inflammatory responses in small vessels in the development of cardiovascular diseases, including hypertension. The study identifies various complex molecular processes that contribute to microvascular damage, such as oxidative stress, inflammasome activation, immune-mediated responses, and protein misfolding. The researchers suggest that monoclonal antibodies targeting inflammatory cytokines and epigenetic drugs show promise in reducing microvascular inflammation and associated cardiovascular diseases. This comprehensive report provides insights into the mechanisms underlying microvascular inflammation and offers potential therapeutic strategies for vascular injury in cardiovascular disease. [Extracted from the article]