Shenzhen Campus of Sun Yat-sen University Researchers Release New Study Findings on Nanodiscs (Molecular Dynamics and In Vitro Studies Elucidating the Tunable Features of Reconfigurable Nanodiscs for Guiding the Optimal Design of Curcumin...).

Researchers from the Shenzhen Campus of Sun Yat-sen University in China have conducted a study on nanodiscs and their potential for drug delivery. The study focused on the conformational characteristics of Apolipoprotein A-I (apoA-I) peptide analogs (APAs) in nanodisc assembly and their ability to encapsulate curcumin. Molecular dynamic simulations and in vitro assessments were used to evaluate the efficacy of different APA-ND formulations as drug carriers. The findings suggest that APA-NDs have the potential to be a promising platform for drug delivery, with tunable features that can revolutionize nanomedicine. [Extracted from the article]