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Development of a polystyrene-based microplastic model for bioaccumulation and biodistribution study using radiotracing and nuclear analysis method.
- Source :
- Marine Pollution Bulletin; Apr2024, Vol. 201, pN.PAG-N.PAG, 1p
- Publication Year :
- 2024
-
Abstract
- The investigation of micro or nano plastics behavior in the environment is essential to minimize the hazards of such pollutants on humans. While the conventional method requires sophisticated procedures and a lot of animal subjects, the nuclear technique confers a sensitive, accurate, and real-time method using radiolabeled micro or nano plastics as a tracer. In this study, polystyrene sulfonate-based microplastic (PSM) was developed with a size of around 3.6 μm, followed by radiolabeling with iodine-131 (<superscript>131</superscript>I) or zinc-65 (<superscript>65</superscript>Zn) for microplastic radiotracer model. After a stability study in seawater, phosphate buffer saline (PBS), and human serum albumin (HSA) for fifteen days, PSM-<superscript>131</superscript>I remained stable (>90 %), except in HSA (50–60 % after day-9), while PSM-<superscript>65</superscript>Zn was unstable (<50 %). • Microplastic models can be prepared from styrofoam waste. • Iodine-131 and zinc-65 are used for the radiolabeling of micropolystyrene sulfonate. • Iodine-131 labeled micro polystyrene sulfonate is stable in phosphate buffer saline and seawater. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0025326X
- Volume :
- 201
- Database :
- Supplemental Index
- Journal :
- Marine Pollution Bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 176390627
- Full Text :
- https://doi.org/10.1016/j.marpolbul.2024.116283