Researchers from COMSATS University Report on Findings in Biomarkers (Probing Aptamer-mucin 1 Binding Events On Polydopamine@carbon Nanotubes Modified Cellulose Paper Interface Using Speckle Pattern Analysis for Label Free Aptasensing).

Researchers from COMSATS University in Lahore, Pakistan have developed a cellulose paper-based aptasensing protocol for the detection of the cancer biomarker mucin 1 (MUC1). The paper surface was modified using polydopamine modified carbon nanotubes (PDA@CNTS) to create a strong adhesion and binding interface. The researchers used dynamic laser speckle (DLS) analysis to analyze the speckle patterns generated from the cellulose-based paper surface, providing sensitive and accurate analysis of the target biomarker. The paper-based aptasensor demonstrated sensitive and selective detection of MUC1, making it a promising tool for low-cost and portable biological applications. [Extracted from the article]