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A case report of LAI two injection start in a 16-year-old adolescent with severe manic episode and comorbid cannabinoid use disorder.

A case report of LAI two injection start in a 16-year-old adolescent with severe manic episode and comorbid cannabinoid use disorder.

Authors :
Orsolini, Laura
Biagiotti, Sofia Pacini
Martino, Lorenzo Maria
Volpe, Umberto
Source :
Asian Journal of Psychiatry; Apr2024, Vol. 94, pN.PAG-N.PAG, 1p
Publication Year :
2024

Abstract

There is a lack of randomized clinical trials and few studies regarding long-acting injectable antipsychotics (LAIs) in adolescents. Non-adherence, aggressiveness, comorbid substance use disorder and lack of insight may represent the main reasons for starting LAIs. Hereby we describe a 16-year-old male adolescent subject with bipolar type I disorder and comorbid cannabinoid use disorder, successfully treated with two-injection start regimen of LAI aripiprazole. Two-injection start regime of aripiprazole could represent an effective and safe therapeutic option for adolescents with early onset bipolar disorder. • There is a lack of randomized clinical trials regarding LAIs in adolescents. • LAIs display good effectiveness and acceptable tolerability in adolescents with schizophrenia and bipolar disorder. • Non-adherence, aggressiveness, comorbid substance use disorder and lack of insight could benefit from LAIs. • Aripiprazole two-injection start could be an effective and safe therapeutic option for adolescents with bipolar disorder. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
18762018
Volume :
94
Database :
Supplemental Index
Journal :
Asian Journal of Psychiatry
Publication Type :
Academic Journal
Accession number :
176247362
Full Text :
https://doi.org/10.1016/j.ajp.2024.103992