Researcher from Deakin University Reports on Findings in Cancer [Janus Kinase 3 (JAK3): A Critical Conserved Node in Immunity Disrupted in Immune Cell Cancer and Immunodeficiency].

A recent study conducted by researchers from Deakin University in Geelong, Australia, explores the role of Janus Kinase 3 (JAK3) in immune cell development and function. The JAK3 protein tyrosine kinase is crucial for signal transduction in cytokine receptors, and mutations in JAK3 have been linked to both immune cell malignancies and immunodeficiency. The study highlights the conservation of JAK3 mutations and the importance of animal models in understanding the biology and impact of these mutations. For more information, readers can refer to the article published in the International Journal of Molecular Sciences. [Extracted from the article]