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Kruppel-like factor 4, a potential therapeutic agent for colorectal cancer: A bioinformatics analysis.
- Source :
- Drug Week; 3/19/2024, p473-473, 1p
- Publication Year :
- 2024
-
Abstract
- Colorectal cancer is a significant and deadly form of cancer, and new treatment strategies and prognostic markers are needed. This study used bioinformatics analysis to identify differentially expressed genes and interaction networks in colorectal cancer. The Kruppel-like factor 4 (KLF4) gene was identified as a potential biomarker and drug target, as it showed a positive correlation with immune cells and was associated with poor prognosis. However, further experiments are needed to validate its role as a biomarker. Targeting the KLF4 gene with small-molecule inhibitors may be an effective strategy for early diagnosis and treatment of colorectal cancer. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 15316440
- Database :
- Supplemental Index
- Journal :
- Drug Week
- Publication Type :
- Periodical
- Accession number :
- 176050465