Reports on Tissue Engineering from International University Provide New Insights (Fabrication of Novel Bone Substitute Alginate - N,o-carboxymethyl Chitosan - Aldehyde Hyaluronic Acid - Biphasic Calcium Phosphate for Bone Regeneration).

A study conducted at International University in Ho Chi Minh City, Vietnam, explores the fabrication of hydrogel composites for bone tissue engineering. The researchers developed a mineralized hydrogel composite using alginate, N,O-carboxymethyl chitosan (NOCC), aldehyde hyaluronic acid (AHA), and biphasic calcium phosphate (BCP). The hydrogel composite demonstrated suitable properties for bone regeneration, including a suitable degradation rate, appropriate pore size, favorable cytocompatibility, high compressive strength, and the ability to support cell proliferation. In vitro and in vivo studies confirmed the effectiveness of the hydrogel composite in promoting bone healing. [Extracted from the article]