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New Prurigo Findings from Johns Hopkins University School of Medicine Published (Dysregulation of the Skin-Liver Axis in Prurigo Nodularis: An Integrated Genomic, Transcriptomic, and Population-Based Analysis).
- Source :
- Cancer Weekly; 3/11/2024, p879-879, 1p
- Publication Year :
- 2024
-
Abstract
- A study conducted by Johns Hopkins University School of Medicine has found a link between prurigo nodularis (PN), a chronic inflammatory skin disease, and liver disease. The study revealed that PN patients had a higher risk of developing various liver conditions compared to healthy controls. Further analysis showed dysregulation of genes related to hepatic failure in PN patients. A subsequent genome-wide association study identified shared genetic variations between PN and liver disease. These findings suggest a dysregulation of the skin-liver axis in PN patients and may help identify future therapeutic targets. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 10717218
- Database :
- Supplemental Index
- Journal :
- Cancer Weekly
- Publication Type :
- Periodical
- Accession number :
- 175902380