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Synthesis and Trace-Level Quantification of Mutagenic and Cohort-of-Concern Ciprofloxacin Nitroso Drug Substance-Related Impurities (NDSRIs) and Other Nitroso Impurities Using UPLC-ESI-MS/MSMethod Optimization Using I‑Optimal Mixture Design.

Authors :
Nakka, Srinivas
Katari, Naresh Kumar
Muchakayala, Siva Krishna
Jonnalagadda, Sreekantha Babu
Manabolu Surya, Surendra Babu
Source :
ACS Omega; 2/27/2024, Vol. 9 Issue 8, p8773-8788, 16p
Publication Year :
2024

Details

Language :
English
ISSN :
24701343
Volume :
9
Issue :
8
Database :
Supplemental Index
Journal :
ACS Omega
Publication Type :
Academic Journal
Accession number :
175718558
Full Text :
https://doi.org/10.1021/acsomega.3c05170