Research from University of North Carolina Wilmington Has Provided New Data on Biological Factors (Karenia brevis Extract Induces Cellular Entry through Distinct Mechanisms in Phagocytic RAW 264.7 Macrophages versus Non-Phagocytic Vero...).

A recent study conducted by researchers at the University of North Carolina Wilmington has provided new data on the biological factors of Karenia brevis, a marine dinoflagellate. The study found that the extract from this organism, which contains chlorophyll a and pheophytin a, enters phagocytic RAW 264.7 macrophages and non-phagocytic Vero kidney cells through distinct mechanisms. The researchers also observed that the extract stimulated phagocytic responses in the macrophages and potentially suppressed their immune function. This study highlights the importance of understanding the cellular uptake and mechanisms of action of fluorescing algae extracts for future drug discovery efforts. [Extracted from the article]