Data on Antibiotics Reported by Researchers at University of South Florida (Drug Discovery in the Field of b-Lactams: An Academic Perspective).

A study conducted by researchers at the University of South Florida explores the field of b-Lactams, which are the most commonly prescribed class of antibiotics. The study focuses on the mechanisms of antibiotic resistance, particularly the production of b-lactamase enzymes that can hydrolyze b-lactam antibiotics. The researchers summarize recent findings on b-lactamases and cell wall transpeptidases, which are evolutionarily and functionally connected enzymes. The study highlights the development of new inhibitors against both transpeptidases and b-lactamases, as well as the potential for non-b-lactam transpeptidase inhibitors to usher in the next phase of drug discovery. [Extracted from the article]