Estimating organ dose with optimized peak dose index in cone-beam CT scans.

• We developed conversion coefficients to estimate organ doses for CBCT scanners. • The conversion coefficients were derived from the appropriate peak dose indices. • The organ doses were well estimated with a 14% error across various CBCT scanners. Organ dose evaluation is important for optimizing cone beam computed tomography (CBCT) scan protocols. However, an evaluation method for various CBCT scanners is yet to be established. In this study, we developed scanner-independent conversion coefficients to estimate organ doses using appropriate peak dose (f(0)) indices. This study included various scanners (angiography scanners and linear accelerators) and protocols for the head and body (thorax, abdomen, and pelvis) scan regions. f(0) was measured at five conventional positions (center position (f(0) c) and four peripheral positions (f(0) p) at 90° intervals) in the CT dose index (CTDI) phantom. To identify appropriate measurement positions for organ dose estimation, various f(0) indices were considered. Organ doses were measured by using optically stimulated luminescence dosimeters positioned in an anthropomorphic phantom. Thereafter, the conversion coefficients were calculated from each obtained f(0) value and organ or tissue dose using a linear fit for all scanners, and the coefficient of variation (CV) of the conversion coefficients was calculated for each organ or tissue. The f(0) index with the minimum CV value was proposed as the appropriate index. The appropriate f(0) index was determined as f(0) c for the body region and a maximum of four f(0) p values for the head region. Using the proposed conversion coefficients based on the appropriate f(0) index, the organ/tissue doses were well estimated with a mean error of 14.2% across all scanners and scan regions. The proposed scanner-independent coefficients are useful for organ dose evaluation using CBCT scanners. [ABSTRACT FROM AUTHOR]