Bacterial patterns and antibiotic sensitivity in septic patients treated with culture-based antibiotics in intensive care.

Objective: This study aims to determine the pattern of germs and antibiotic sensitivity in septic patients treated with culture-based antibiotics. Design: This study was designed for observational-descriptive retrospective. Setting: The medical record of Dr. Wahidin Sudirohusodo Hospital from January 2018 to January 2022. Patient and participants: All patients who were diagnosed with sepsis and had data on bacterial culture and treatment with antibiotics. Interventions: We took blood culture data of patients diagnosed with sepsis from medical records. Measurement and results: The pattern of bacteria found was Gram-negative bacteria, with the most abundant bacteria being Burkholderia cepacia (37.93%), followed by Acinetobacter baumannii (24.14%), and Klebsiella pneumoniae (10.34%). The highest antibiotic sensitivity was obtained for tigecycline with 88.89% followed by levofloxacin with 78.57%. The lowest antibiotic sensitivity was found in ampicillin, ampicillin/sulbactam, and cefoperazone/sulbactam as much as 0% or all of these antibiotics showed results that were resistant to culture results. Conclusions: Gram-negative bacteria are the main cause of septic patients with varying antibiotic sensitivity depending on the type of antibiotic used. [ABSTRACT FROM AUTHOR]