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Anti-inflammatory and anti-cancer potential of pterostilbene: A review.

Authors :
Surien, Omchit
Masre, Siti Fathiah
Basri, Dayang Fredalina
Ghazali, Ahmad Rohi
Source :
Asian Pacific Journal of Tropical Biomedicine; Dec2023, Vol. 13 Issue 12, p497-506, 10p
Publication Year :
2023

Abstract

Pterostilbene is a natural compound that can be found in various food plants such as blueberries, grapes, and peanuts. It has also been reported to be extracted from Pterocarpus indicus, a tree species native to India and Southeast Asia. Pterostilbene exhibits various pharmacological activities such as antioxidants, anti-proliferation, anti-microbial, and anti-inflammatory activities with favorable pharmacokinetic properties, such as high oral bioavailability and longer half-life. The anti-inflammatory effect of pterostilbene has been reported to contribute to its therapeutic effects in many chronic inflammatory diseases. Besides, pterostilbene has anti-cancer activity on various types of cancers due to its ability to induce cell cycle arrest and apoptosis. Hence, in this review, we discuss the anti-inflammatory and anti-cancer activities of pterostilbene in preclinical studies. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
22211691
Volume :
13
Issue :
12
Database :
Supplemental Index
Journal :
Asian Pacific Journal of Tropical Biomedicine
Publication Type :
Academic Journal
Accession number :
174847941
Full Text :
https://doi.org/10.4103/2221-1691.391155