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Efficacy of different 8 h time-restricted eating schedules on visceral adipose tissue and cardiometabolic health: A study protocol.

Authors :
Dote-Montero, Manuel
Merchan-Ramirez, Elisa
Oses, Maddi
Echarte, Jon
Clavero-Jimeno, Antonio
Alcantara, JMA
Camacho-Cardenosa, Alba
Cupeiro, Rocío
Rodríguez-Miranda, María de las Nieves
López-Vázquez, Alejandro
Amaro-Gahete, Francisco J.
González Cejudo, María Trinidad
Martin-Olmedo, Juan J.
Molina-Fernandez, Marcos
García Pérez, Patricia Virginia
Contreras-Bolívar, Victoria
Muñoz-Garach, Araceli
Andreo-López, María C.
Carneiro-Barrera, Almudena
Miranda-Ferrúa, Emiliano
Source :
Nutrition, Metabolism & Cardiovascular Diseases; Jan2024, Vol. 34 Issue 1, p177-187, 11p
Publication Year :
2024

Abstract

To investigate the efficacy and feasibility of three different 8 h time-restricted eating (TRE) schedules (i.e., early, late, and self-selected) compared to each other and to a usual-care (UC) intervention on visceral adipose tissue (VAT) and cardiometabolic health in men and women. Anticipated 208 adults (50% women) aged 30–60 years, with overweight/obesity (25 ≤ BMI<40 kg/m<superscript>2</superscript>) and with mild metabolic impairments will be recruited for this parallel-group, multicenter randomized controlled trial. Participants will be randomly allocated (1:1:1:1) to one of four groups for 12 weeks: UC, early TRE, late TRE or self-selected TRE. The UC group will maintain their habitual eating window and receive, as well as the TRE groups, healthy lifestyle education for weight management. The early TRE group will start eating not later than 10:00, and the late TRE group not before 13:00. The self-selected TRE group will select an 8 h eating window before the intervention and maintain it over the intervention. The primary outcome is changes in VAT, whereas secondary outcomes include body composition and cardiometabolic risk factors. This study will determine whether the timing of the eating window during TRE impacts its efficacy on VAT, body composition and cardiometabolic risk factors and provide insights about its feasibility. • This study will determine whether the timing of TRE impacts its efficacy. • The study will provide evidence about the effects of TRE on ectopic fat. • Our study is powered to investigate potential sex differences in TRE effects. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09394753
Volume :
34
Issue :
1
Database :
Supplemental Index
Journal :
Nutrition, Metabolism & Cardiovascular Diseases
Publication Type :
Academic Journal
Accession number :
174409643
Full Text :
https://doi.org/10.1016/j.numecd.2023.09.014