Data on Obesity, Fitness and Wellness Reported by Researchers at University of Washington (Cyp2d6 Activity Is Correlated With Changes In Plasma Concentrations of Taurocholic Acid During Pregnancy and Postpartum In Cyp2d6 Extensive Metabolizerss).

A recent report from the University of Washington discusses the correlation between CYP2D6 activity and changes in plasma concentrations of taurocholic acid during pregnancy and postpartum in CYP2D6 extensive metabolizers. The study found that the bile acid plasma metabolome differs between pregnancy and postpartum, and taurocholic acid may impact CYP2D6 activity during pregnancy. These findings contribute to our understanding of the metabolism of drugs and the potential effects of pregnancy on drug metabolism. The research was funded by the NIH and has been peer-reviewed. [Extracted from the article]