The Effectiveness of Mangosteen Peel (Garcinia Mangostana L) Extract Mouthwash on Reducing Gingival Inflammation.

Gingival inflammation or gingivitis is an inflammation of the gingiva caused by deposits of supragingival plaque characterized by changes in clinical features. Treatment of gingivitis consists of mechanical procedure through scaling and root planing, but mechanical procedure alone sometimes is not effective, therefore mechanical treatment should be combined with adjunctive therapy. Mangosteen peel is an ingredient that has anti-inflammatory and antibacterial properties. This study aims to determine the effectiveness of mangosteen peel extract mouthwash in reducing gingival inflammation. This study was conducted using a double-blind simple randomized-controlled trial. A total of 32 subjects with gingivitis were randomly assigned into 4 different groups, namely group I placebo, group II concentration of 2%, group III concentration of 4%, and group IV concentration of 6%. All subjects were given scaling as initial treatment then, the Modified Gingival Index (MGI) and Sulcular Bleeding Index (SBI) score were measured on the 1st and 8th days. The MGI and SBI scores are reduced in all groups on the 8th day. A significant MGI score reduction was seen in concentration 2% and concentration 6% compared to negative control and no significant differences between the two concentrations Mangosteen peel extract mouthwash can reduce gingival inflammation with the highest reduction seen at concentrations of 2% and 6% viewed based on the MGI parameter. [ABSTRACT FROM AUTHOR]