Southeast University Researcher Provides New Insights into Liposomes [Astragalus polysaccharide liposome nanoparticles mediate fatty acid translocase (FAT)/CD36 to improve fatty acid metabolism and regulate glucocorticoid receptor levels in...].

A study conducted by researchers at Southeast University in China has found that Astragalus polysaccharide (APS) combined with liposome nanoparticles (APS-nano) can improve fatty acid metabolism and regulate glucocorticoid receptor levels in diabetic cardiomyopathy (DCM). The study involved 50 rats and compared the effects of APS-nano with other groups. The results showed that APS-nano had the highest level of insulin and the lowest blood sugar levels among all groups. It also decreased the levels of total cholesterol, triglyceride, and free fatty acid compared to the control and model groups. The study concluded that APS-nano can regulate FAT/CD36 expression and improve fatty acid metabolism, thereby lowering myocardial tissue metabolism and inhibiting glucocorticoid receptor levels. [Extracted from the article]