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An effective approach for preparing supramolecular polymers at high concentration.
- Source :
- Drug Week; 12/8/2023, p344-344, 1p
- Publication Year :
- 2023
-
Abstract
- A research team from Chiba University in Japan has developed a novel approach for preparing supramolecular polymers (SPs) at high concentrations. SPs are molecular assemblies composed of non-covalently bonded small molecules and have high recyclability. However, the formation of crystalline polymorphic states can reduce the solubility of drug molecules. To overcome this issue, the researchers used a supramolecular coformer approach, which significantly improved the solubility of the drug molecule without affecting its ability to form SPs. This approach has the potential to facilitate large-scale production of SPs and contribute to the development of recyclable plastics. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 15316440
- Database :
- Supplemental Index
- Journal :
- Drug Week
- Publication Type :
- Periodical
- Accession number :
- 173931531