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Phrenic Nerve Stimulation for Acute Respiratory Failure.
- Source :
- Respiratory Care; Dec2023, Vol. 68 Issue 12, p1736-1747, 12p
- Publication Year :
- 2023
-
Abstract
- Diaphragm inactivity during invasive mechanical ventilation leads to diaphragm atrophy and weakness, hemodynamic instability, and ventilatory heterogeneity. Absent respiratory drive and effort can, therefore, worsen injury to both lung and diaphragm and is a major cause of failure to wean. Phrenic nerve stimulation (PNS) can maintain controlled levels of diaphragm activity independent of intrinsic drive and as such may offer a promising approach to achieving lung and diaphragm protective ventilatory targets. Whereas PNS has an established role in the management of chronic respiratory failure, there is emerging interest in how its multisystem putative benefits may be temporarily harnessed in the management of invasively ventilated patients with acute respiratory failure. [ABSTRACT FROM AUTHOR]
- Subjects :
- RESPIRATORY insufficiency
ARTIFICIAL respiration
PHRENIC nerve
Subjects
Details
- Language :
- English
- ISSN :
- 00201324
- Volume :
- 68
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- Respiratory Care
- Publication Type :
- Academic Journal
- Accession number :
- 173910587
- Full Text :
- https://doi.org/10.4187/respcare.11439