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Effects of exercise training on cancer patients undergoing neoadjuvant treatment: A systematic review.

Authors :
Malveiro, Carla
Correia, Inês R.
Cargaleiro, Catarina
Magalhães, João P.
de Matos, Leonor Vasconcelos
Hilário, Sofia
Sardinha, Luís B.
Cardoso, Maria João
Source :
Journal of Science & Medicine in Sport; Nov2023, Vol. 26 Issue 11, p586-592, 7p
Publication Year :
2023

Abstract

This systematic review aimed to analyze the effects of different exercise protocols on physical fitness (cardiorespiratory fitness, muscle strength, and body composition), quality of life, cancer-related fatigue, and sleep quality in patients with different types of cancer undergoing neoadjuvant treatment. Systematic review. A comprehensive search of existing literature was carried out using four electronic databases: PubMed, Scopus, Web of Science, and Cochrane Library (published until October 19, 2022). All databases were searched for randomized controlled trials, quasi-experimental investigations, and pre-post investigations assessing the effects of exercise in cancer patients during neoadjuvant treatment. Excluded articles included multicomponent interventions, such as exercise plus diet or behavioral therapy, and investigations performed during adjuvant treatment or survivorship. The methodological quality of each study was assessed using the Physiotherapy Evidence Database (PEDro) scale. Twenty-seven trials involving 999 cancer patients were included in this review. The interventions were conducted in cancer patients undergoing neoadjuvant treatment for rectal (n = 11), breast (n = 5), pancreatic (n = 4), esophageal (n = 3), gastro-esophageal (n = 2), and prostate (n = 1) cancers, and leukemia (n = 1). Among the investigations included, 14 utilized combined exercise protocols, 11 utilized aerobic exercise, and two utilized both aerobic and resistance training separately. Exercise interventions appeared to improve cardiorespiratory fitness, muscle strength, body composition, and quality of life, although many investigations lacked a between-group analysis. Despite limited evidence, exercise interventions applied during neoadjuvant treatment demonstrate promising potential in enhancing cardiorespiratory fitness, muscle strength, body composition, and overall quality of life. However, a scarcity of evidence remains on the effects of exercise on cancer-related fatigue and sleep quality. Further research with high-quality randomized controlled trials is warranted. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14402440
Volume :
26
Issue :
11
Database :
Supplemental Index
Journal :
Journal of Science & Medicine in Sport
Publication Type :
Academic Journal
Accession number :
173807178
Full Text :
https://doi.org/10.1016/j.jsams.2023.08.178