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Exposure estimates of parabens from personal care products compared with biomonitoring data in human hair from Northeast China.
- Source :
- Ecotoxicology & Environmental Safety; Nov2023, Vol. 267, pN.PAG-N.PAG, 1p
- Publication Year :
- 2023
-
Abstract
- Parabens (PBs), a class of endocrine-disrupting chemicals (EDCs), are extensively used as additives in personal care products (PCPs); however, distinguishing between endogenous and exogenous contamination from PCPs in hair remains a challenge. We conducted a comprehensive analysis of the levels, distribution patterns, impact factors, and sources of PBs in 119 human hair samples collected from Changchun, northeast China. The detection rates of methylparaben (MeP), propylparaben (PrP), and ethylparaben (EtP) in hair samples were found to be 100%. The concentration of PBs in hair followed the order of MeP (57.48 ng/g) > PrP (46.40 ng/g) > EtP (6.80 ng/g). The concentration of PrP in female hair was significantly higher (65.38 ng/g) than that observed in male hair (7.82 ng/g) (p < 0.05). The levels of excretion rates of MeP (ER MeP) and excretion rates of PrP (ER PrP) in the hair-dying samples (ER MeP : 17.89 ng/day; ER PrP : 14.15 ng/day) were found to be 2.52 and 2.40 times higher, respectively, compared to the non-hair-dying samples (ER MeP : 7.09 ng/day; ER PrP : 6.05 ng/day). However, the system exposure dosage (SED) results revealed that although hair dyes exhibited higher PBs, human exposure was found to be lower than certain PCPs. The results of the correlation analysis revealed that toner, face cream, body lotion, and hair conditioner were identified as the primary sources of PBs in male hair. Furthermore, the human exposure resulting from the utilization of female hair dye and serum exhibited a positive correlation with hair ER MeP and ER PrP levels, indicating in the screening of samples, excluding hair samples using hair dye and haircare essential oil can effectively avoid the interference caused by exogenous contamination from PCPs. • MeP, PrP, and EtP detection rates were 100%. • PB levels of ER in non-hair-dying samples were lower than in hair-dying samples. • The SED levels in hair dye were smaller than in other PCP. • Using dyes and serums affected the detection of endogenous PB contamination in hair. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01476513
- Volume :
- 267
- Database :
- Supplemental Index
- Journal :
- Ecotoxicology & Environmental Safety
- Publication Type :
- Academic Journal
- Accession number :
- 173700914
- Full Text :
- https://doi.org/10.1016/j.ecoenv.2023.115635