Research Conducted at Harbin Medical University Has Updated Our Knowledge about Armadillo Domain Proteins (Neuroepithelial Cell-transforming 1 Promotes Cardiac Fibrosis Via the Wnt/8-catenin Signaling Pathway).

A recent study conducted at Harbin Medical University in Heilongjiang, China has provided new insights into the role of Armadillo Domain Proteins in cardiac fibrosis. The researchers found that the neuroepithelial cell-transforming gene 1 protein (NET1) was significantly increased in a mouse model of cardiac fibrosis. They also discovered that NET1 promotes the expression of beta-catenin, a protein involved in fibroblast proliferation and migration. The study suggests that NET1 may be a potential therapeutic target for treating cardiac fibrosis. [Extracted from the article]