Mitochondrial perturbation of the epithelium causes microbial dysbiosis and unresolved tissue injury in intestinal inflammation (Updated October 11, 2023).

"Furthermore, selective colonization of GF Hsp60{Delta}/{Delta}IEC mice with OMM12 induces metabolic injury and Bacteroides caecimuris expansion, which generates metabolic injury in mono-colonized mice. Bacteroidaceae, Bacteroides, Bacteroidetes, Gram-Negative Bacteria, Gram-Negative Bacteria - Bacteroides, Health and Medicine, Inflammation While metabolic perturbation causes self-resolving tissue injury, inflammation is accelerated in the susceptible host (Hsp60{Delta}/{Delta}IEC;Il10-/-). [Extracted from the article]