New Borrelia burgdorferi Study Findings Have Been Reported by Investigators at Indiana University (Organization and Replicon Interactions Within the Highly Segmented Genome of Borrelia Burgdorferi).

Using chromosome conformation capture assays, we determined the interactions within the chromosome, between the chromosome and plasmids, and between the plasmids. We found that Smc and the Smc-like MksB protein mediate long-range interactions on the chromosome, but they minimally affect plasmid-chromosome or plasmid-plasmid interactions. [Extracted from the article]