Data on Helicobacter pylori Discussed by Researchers at Yale University (Isotope Tracing Reveals Bacterial Catabolism of Host-derived Glutathione During Helicobacter Pylori Infection).

To monitor glutathione dynamics during infection, we developed an isotope-labeling strategy that can track host-derived glutathione in H. pylori-infected cells. Consistent with bacterial catabolism of host GSH, levels of oxidized GSH did not increase during H. pylori infection, and exogenous antioxidants were unable to restore the GSH content of infected cells. [Extracted from the article]