EP052 CLINICAL OUTCOMES IN DIABETIC FOOT PATIENTS WITH AND WITHOUT CANCER ADMITTED FOR INTERVENTIONAL PROCEDURES.

Aim: Diabetic Foot Syndrome (DFS) is associated with a high risk of cardiovascular morbidity and major amputation (MA). Likewise, cancer is a well-established risk for cardiovascular disease. Our aim was to assess if DFS patients with cancer have a worse cardiovascular profile and surgical outcomes compared to DFS patients without cancer. Method: We retrospectively analyzed the charts data of 223 consecutive DFS patients [M:166/F:57, age: 69.6±10.4,T2DM 94.66%/T1DM 5.4%] admitted between January 2019 and December 2021 in our Department for interventional procedures (Revascularization and/or foot surgery). Prevalence of cancer, cardiovascular pathologies, MA and re-intervention were derivated. Results / Discussion: Cancer was observed in 47 (21.1%) DFS patients. Patients with cancer were older (71.5 vs 68 yrs, p<0.01) and with a longer history of diabetes (24.5 vs 19 yrs,p<0.05). Major cardiovascular events, atrial fibrillation and renal failure prevalence didn't differ between patients with and without cancer. After a median time of 5 months, reoperation was performed in 35.4% of patients, without any difference between cancer+ and cancer- DFS. Globally, MA prevalence was 9.6%. Although, MA prevalence did not differ between patients with and without cancer, patients with blood cancer (n=9) showed a higher prevalence of MA than those with solid tumors (33.3% vs 5.1%, p<0.05) and those without cancer (9.7%, p<0.05). Conclusion: Cardiovascular profile, surgical outcome and reoperation rate didn't differ between DFS patients with and without cancer. More studies are needed to confirm that DFS patients with blood tumors could present higher risk of MA. [ABSTRACT FROM AUTHOR]