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Pulse-echo ultrasound measurement in osteoporosis screening: a pilot study in older patients.
- Source :
- Aging Clinical & Experimental Research; Jun2023, Vol. 35 Issue 6, p1221-1230, 10p
- Publication Year :
- 2023
-
Abstract
- Background: A mere 25% of patients who need treatment for osteoporosis receive appropriate therapy, partly due to the time-consuming and stressful diagnostic workup for older patients with functional decline. Aims: The purpose of the present study was to investigate the accuracy of pulse-echo ultrasound measurement of the lower leg for the detection of osteoporosis in older patients, and evaluate the effect of a proposed diagnostic algorithm. Methods: Cortical thickness and the so-called density index (DI) were measured prospectively on the lower leg with a pulse-echo ultrasound (PEUS) device. The accuracy of the device was compared with dual-energy X-ray absorptiometry (DXA) of the hip. We calculated algorithms combining FRAX® scores and PEUS measures as a guide for specific treatment of osteoporosis. Results: Three hundred and thirty-three patients aged on average 81 years (82.1% women, 275/333) were included in the study. The sensitivity of the ultrasound device versus DXA for the detection of osteoporosis was 94.4% (84/89), and the specificity was 59% (144/247). The gender-specific sensitivity was 96.2% (75/78) for women and 81.8% (9/11) for men. Discussion: Clinical decisions for the specific treatment of osteoporosis could be based on the proposed algorithm, without additional DXA measurements, in 90.9% (303/333) of the patients. Conclusion: Older patients with a similar risk profile as in our study population may benefit from PEUS, as it is a non-invasive, cost-effective, and efficient diagnostic tool with high accuracy in screening patients for osteoporosis and the risk of fractures. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15940667
- Volume :
- 35
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Aging Clinical & Experimental Research
- Publication Type :
- Academic Journal
- Accession number :
- 163824281
- Full Text :
- https://doi.org/10.1007/s40520-023-02404-z